Figure 7
From: An integrated Bayesian analysis of LOH and copy number data
Example of copy number event classification. The plot shows the estimated log2ratio values (given by mBPCR), as function of the estimated percentage of cells bearing the aberration (given by FISH). The aberrations considered in the graph were identified by FISH on 18 patients of [37, 38], for a total of 133 interrogated genomic regions. The copy number changes are classified as loss, gain or normal, using the results given by the FISH. For the normal regions, we set the percentage as 100%. The estimated log2ratio is the one of the genomic region interrogated by FISH. We can observe that only the aberrations borne in at least 60% of the cells are clearly separated.