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Table 5 The performance of GPCR-SVMFS and GPCRPred at subfamily level

From: Classification of G-protein coupled receptors based on support vector machine with maximum relevance minimum redundancy and genetic algorithm

Class A subfamilies Number of proteins Q i /Q(%)
   GPCRPred[14] GPCR-SVMFS a
Amine 221 99.10 100.0
Peptide 381 99.70 99.21
Hormone 25 100.0 100.0
Rhodopsin 183 98.90 99.45
Olfactory 87 100.0 100.0
Prostanoid 38 100.0 100.0
Nucleotide 48 85.40 93.75
Cannabis 11 100.0 90.91
Platelet activating factor 4 100.0 100.0
Gonadotrophin releasing hormone 10 100.0 100.0
Thyrotropin releasing hormone 7 85.70 85.71
Melatonin 13 100.0 100.0
Viral 17 33.30 76.47
Lysospingolipids 9 58.80 100.0
Overall 1054 97.30 98.77
  1. a In order to consistent with evaluation method of GPCRPred, 2-fold cross-validation is utilized.