TY - JOUR AU - Bailly-Bechet, Marc AU - Braunstein, Alfredo AU - Pagnani, Andrea AU - Weigt, Martin AU - Zecchina, Riccardo PY - 2010 DA - 2010/06/29 TI - Inference of sparse combinatorial-control networks from gene-expression data: a message passing approach JO - BMC Bioinformatics SP - 355 VL - 11 IS - 1 AB - Transcriptional gene regulation is one of the most important mechanisms in controlling many essential cellular processes, including cell development, cell-cycle control, and the cellular response to variations in environmental conditions. Genes are regulated by transcription factors and other genes/proteins via a complex interconnection network. Such regulatory links may be predicted using microarray expression data, but most regulation models suppose transcription factor independence, which leads to spurious links when many genes have highly correlated expression levels. SN - 1471-2105 UR - https://doi.org/10.1186/1471-2105-11-355 DO - 10.1186/1471-2105-11-355 ID - Bailly-Bechet2010 ER -