Figure 1
From: Interaction prediction and classification of PDZ domains
Representative structure of a PDZ domain in complex with its ligand. (a) The common representation of a PDZ domain (α-1 syntrophin) with a peptide (in its stick form) in its binding pocket. Peptide positions -1 and -3 (blue) point towards to the solvent, the positions 0 and -2 (pink) head towards to the binding pocket (b) The interaction of the peptide with αB helix and conserved GLGF segment (here it is GLGI) of the βA-βB loop (PDB ID:2PDZ).