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Table 4 Comparison of the p53 consensus motif distributions in the four sets of putative p53 target genes obtained by the MVDM method [10], gene expression analysis [17], Chip-PET analysis [19] and our nonlinear model in this work.

From: Quantitative model for inferring dynamic regulation of the tumour suppressor gene p53

# of Perfect match

MVDM

GRA

Chip-PET

Nonlinear

0 p53 motif (5 k)

0.41

0.24

0.28

0.22

1 p53 motif (5 k)

0.22

0.38

0.32

0.33

2 p53 motif (5 k)

0.24

0.20

0.25

0.23

> 2 p53 motif (5 k)

0.14

0.18

0.16

0.20

0 p53 motif (10 k)

0.25

0.08

0.06

0.05

1 p53 motif (10 k)

0.14

0.19

0.24

0.15

2 p53 motif (10 k)

0.20

0.27

0.23

0.22

> 2 p53 motif (10 k)

0.41

0.46

0.47

0.58