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Table 3 Biological terms characterizing factor 1 and 2

From: A factor model to analyze heterogeneity in gene expression

FACTOR1

GO ID

GO Term

Size

Count

Pvalue

GO.0007051

spindle organization

6

2

8.20E-03

GO.0050931

pigment cell differentiation

7

2

0.011

GO.0000279

M phase of meiotic cell cycle

79

6

0.012

GO.0000079

regulation of cyclin dependent protein kinase activity

9

2

0.019

GO.0016570

histone modification

13

2

0.038

GO.0015698

inorganic anion transport

53

4

0.039

GO.0007156

homophilic cell adhesion

32

3

0.041

Kegg ID

Kegg pathway

Size

Count

Pvalue

map05216

Thyroid cancer

11

2

0.020

map05130

Pathogenic Escherichia coli infection

12

2

0.024

map04520

Adherens junction

31

3

0.024

FACTOR2

GO ID

GO Term

Size

Count

Pvalue

GO.0006195

purine nucleotide catabolic process

5

3

2.23E-05

GO.0030168

platelet activation

7

3

7.65E-05

GO.0007051

spindle organization

6

2

2.55E-03

GO.0007596

blood coagulation

24

3

3.76E-03

GO.0030336

negative regulation of cell migration

12

2

0.011

GO.0032879

regulation of localization

103

5

0.012

GO.0001775

cell activation

74

4

0.016

GO.0001890

placenta development

18

2

0.023

GO.0017038

protein import

49

3

0.027

GO.0006403

RNA localization

22

2

0.034

GO.0006816

calcium ion transport

56

3

0.038

Kegg ID

Kegg pathway

Size

Count

Pvalue

map00230

Purine metabolism

64

4

0.013

  1. Enrichment tests were performed on the genes contributing the more to the construction of factor 1 and 2 using the GO BP terms and Kegg pathways. For each enriched term, the identifier (ID), the bioligical term, the size of the whole list of genes related to the term (size), the number of genes in the sub-list related to the term (count), the pvalue of the test.