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Table 3 Biological terms characterizing factor 1 and 2

From: A factor model to analyze heterogeneity in gene expression

FACTOR1
GO ID GO Term Size Count Pvalue
GO.0007051 spindle organization 6 2 8.20E-03
GO.0050931 pigment cell differentiation 7 2 0.011
GO.0000279 M phase of meiotic cell cycle 79 6 0.012
GO.0000079 regulation of cyclin dependent protein kinase activity 9 2 0.019
GO.0016570 histone modification 13 2 0.038
GO.0015698 inorganic anion transport 53 4 0.039
GO.0007156 homophilic cell adhesion 32 3 0.041
Kegg ID Kegg pathway Size Count Pvalue
map05216 Thyroid cancer 11 2 0.020
map05130 Pathogenic Escherichia coli infection 12 2 0.024
map04520 Adherens junction 31 3 0.024
FACTOR2
GO ID GO Term Size Count Pvalue
GO.0006195 purine nucleotide catabolic process 5 3 2.23E-05
GO.0030168 platelet activation 7 3 7.65E-05
GO.0007051 spindle organization 6 2 2.55E-03
GO.0007596 blood coagulation 24 3 3.76E-03
GO.0030336 negative regulation of cell migration 12 2 0.011
GO.0032879 regulation of localization 103 5 0.012
GO.0001775 cell activation 74 4 0.016
GO.0001890 placenta development 18 2 0.023
GO.0017038 protein import 49 3 0.027
GO.0006403 RNA localization 22 2 0.034
GO.0006816 calcium ion transport 56 3 0.038
Kegg ID Kegg pathway Size Count Pvalue
map00230 Purine metabolism 64 4 0.013
  1. Enrichment tests were performed on the genes contributing the more to the construction of factor 1 and 2 using the GO BP terms and Kegg pathways. For each enriched term, the identifier (ID), the bioligical term, the size of the whole list of genes related to the term (size), the number of genes in the sub-list related to the term (count), the pvalue of the test.