Figure 5

Statistical characterization of hydrophobicity (A), bulkiness (B), and amino acid codon number (C) for pentapeptide sets with different frequencies in the universal proteome. The boxplots show the distribution of the values of each physico-biochemical factor for each set of pentapeptides. The line within each box represents the median value. The top and bottom of each box represent the 75th and 25th percentile, respectively. The whiskers show the range of values that are not considered to be outliers. Outliers are plotted individually as plus signs. The p-values among the different classes of 5-mers for hydrophobicity, bulkiness, and amino acid codon number were all less than 0.001, indicating in each case that the means of the different sets are different.