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Figure 3 | BMC Bioinformatics

Figure 3

From: Simultaneous prediction of transcription factor binding sites in a group of prokaryotic genomes

Figure 3

Flowchart of the main steps of the eGLECLUBS algorithm. (A). We extract upstream inter-operonic sequences of operons in each COOR to form a set of sequences. (B). For each sequence set, we predict a total of T motifs using multiple motif-finding tools. (C). We construct two motif similarity graphs G1 and G2 using a low and a high motif similarity score cut-offs α and β, respectively, and cut G2 into dense subgraphs using MCL. We construct G3 and cluster it into dense subgraphs using MCL. (D). We induce subgraphs s1, s2, ..., s n of G1 using the clusters from G3, and identify quasi-cliques in each of these induced subgraphs.

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