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Table 2 Contributions of the physicochemical properties to BLOSUM matrices.

From: Amino acid "little Big Bang": Representing amino acid substitution matrices as dot products of Euclidian vectors

Properties

1rsvol

2chrg

3achrg

4awrat

5arom

6hdrp

7kbulk

8khdr2

9khdr3

BLOSUM30

12.0

5.7

5.4

10.9

13.4

12.0

11.8

12.7

11.7

BLOSUM62

12.7

6.0

7.6

9.6

14.2

17.7

12.1

15.6

17.1

BLOSUM100

12.0

6.4

7.5

8.9

13.1

16.6

11.4

14.7

16.2

Properties

10khdr4

11kbpr1

12kbpr2

13kaprf

14kbnd1

15kbnd2

16hydro

17mass

18rand

BLOSUM30

11.5

12.3

9.2

5.3

7.2

9.7

10.6

11.6

5.2 ± 1.4

BLOSUM62

17.2

15.5

12.5

5.6

9.0

12.8

13.9

11.6

5.2 ± 1.4

BLOSUM100

16.2

14.9

12.4

5.6

8.8

12.2

13.2

10.8

5.2 ± 1.3

  1. (Contributions are in % see Eq. 9). The property categories are: volume (1rsvol), charge (2chrg, 3achrg), aromaticity (5arom), hydrophobicity (6hdrp, 8khdr2, 9khdr3, 10khdr4, 16hydro), bulkiness (7kbulk), mass (17mass), α-propensity (13kaprf), β-propensity (11kbpr1, 12kbpr2). The last column 18rand is a simulated "random" property.