Visualization of the overall orientation and prediction results on CCD-IBD complex PDB: 2b4j. (a) The overall orientation of CCD-IBD complex; (b) Protein-protein interaction predictions of CCD-IBD complex. The orientation of the complex is illustrated by a smooth spline between consecutive alpha carbon positions. Left graph denotes the natural orientation, while the right one illustrates the protein-protein interaction prediction of the complex. In the right graph, blue sphere stands for TP residue, bluetint one stands for FP residue, and gold sphere demonstrates FN residue. All other residues (not shown as colored spheres) are true negatives (TN). Note that the orientation of the complex in the right graph is varied a little to clearly show the predictions of protein interface residues. Additionally each sphere represents an alpha-carbon atom of each residue. We used RasTop http://www.geneinfinity.org/rastop/ software to display the structure of this complex.