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Table 6 Performance of methods on hetero-complexes with sequence alone

From: Sequence-based identification of interface residues by an integrative profile combining hydrophobic and evolutionary information

Method

Type

Ratio

Sen

Prec

F1

Our model

SVM

27.56

42.84

81.96

56.25

Wang and Chen

SVM

34.8**

61.4

45.8

52.5

Res et al.

SVM

16

58.8

26.3

36.3

Koike and Takagi*

SVM

20

28.8

27

27.87

Sikic et al.

RF****

27.5

26

84

39.7

Chen and Jeong

RF

10

70

37.7***

49

ISIS et al.

NN*****

32*

20

61

30.1

Ofran and Rost

NN

40*

0.5*

62*

0.1

  1. *Based on homo-hetero mixed complexes dataset.
  2. **The ratio of interface residues to surface residues.
  3. ***Estimated.
  4. ****Random Forests.
  5. *****Neural Network.
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BMC Bioinformatics

ISSN: 1471-2105

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