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Table 2 Comparison of prediction results for the RTA method, described in this article, and the SMM-align method

From: Prediction of the binding affinities of peptides to class II MHC using a regularized thermodynamic model

  AUC  
MHC allele RTA SMM-Align Number of data
DRB1*0101 0.748 0.702 1203
DRB1*0301 0.843 0.779 474
DRB1*0401 0.779 0.741 457
DRB1*0404 0.829 0.798 168
DRB1*0405 0.823 0.727 171
DRB1*0701 0.813 0.768 310
DRB1*0802 0.806 0.724 174
DRB1*0901 0.752 0.726 117
DRB1*1101 0.829 0.715 359
DRB1*1302 0.882 0.810 179
DRB1*1501 0.792 0.715 365
DRB3*0101 0.960 0.620 102
DRB4*0101 0.820 0.730 181
DRB5*0101 0.772 0.664 343
H2-IAb 0.926 0.913 76
H2-IAd 0.894 0.819 342
H2-IAs 0.891 0.877 126
  1. The RTA results were calculated using the cross-validation sets from Ref. [18]. The SMM-align results were taken from the same reference.