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Table 1 Summary of biological significance of modules based on GO biological process annotations

From: Extracting the abstraction pyramid from complex networks

 

Total Clusters

Avg.

Cluster Size

Avg.

p-value

Pyramabs

(Level 2)

3

723

2.69E-32

Pyramabs

(Level 3)

16

152

2.59E-20

Pyramabs

(Level 4)

72

34

2.58E-14

Pyramabs

(Level 5)

221

10

5.00E-08

Luo et al.a

86

19

9.74E-14

Raddichi et al.a

155

13

3.82E-13

Sales-Pardo et al.

(Level 2) b

77

26

5.45E-14

Sales-Pardo et al.

(Level 3) b

101

11

8.24E-11

Sales-Pardo et al.

(Level 4) b

88

8

6.86E-07

Sales-Pardo et al.

(Level 5) b

12

5

2.12E-04

  1. aBoth Luo et al.'s and Raddichi et al.'s methods could only identify single-level modules.
  2. bIn Sales-Pardo et al.'s method, a higher-level module will not necessarily be further partitioned into lower-level sub-modules. Thus, the number of modules does not necessarily increase as the level goes down (e.g., 88 modules at level 4, but only 12 modules at level 5).
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BMC Bioinformatics

ISSN: 1471-2105

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