Figure 1
From: Global parameter estimation methods for stochastic biochemical systems
mRNA Dynamics Model in Escherichia coli. (A) The mRNA detection system comprises two genetic elements; a fluorescence protein fused with bacteriophage protein (MS2d) and a reporter mRNA containing tandem repeats of MS2-binding sites. The GFP binding site repeats facilitate imaging and quantification of cellular mRNA to single molecular level. (B) The transcriptional model constitutes 3 reactions with 3 rate constants. DNAS represents the silent form, while DNAA represents the activated form