Skip to main content

Table 1 Parameter estimation of RNA dynamics model in E. coli.

From: Global parameter estimation methods for stochastic biochemical systems

Replicates

ML

DFD-CDF

DFD-PDF

 

k 1

k 2

k 3

k 1

k 2

k 3

k 1

k 2

k 3

10

0.0235 (0.0233)a

1.304 (0.3231)a

3.2201 (0.7232)a

0.02

0.1029

0.3643

-

-

-

20

0.0227

0.1095

0.2858

0.0371

0.2124

0.5263

-

-

-

100

0.0362

0.2930

0.5533

0.0273

0.1702

0.4121

-

-

-

10000

0.0279

0.2354

0.4872

0.0276

0.1659

0.4102

0.0273

0.1532

0.3837

  1. Parameter estimates in the mRNA dynamics model in E. coli. The true parameter values are k = [0.0277; 0.1667; 0.4]. The search bound for the optimization algorithm was [0,5].
  2. a DE optimization performed with 100 population members and 20,000 generations
Back to article page

BMC Bioinformatics

ISSN: 1471-2105

Contact us