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Table 3 Parameter estimation of full yEGFP model in S. cerevisiae.

From: Global parameter estimation methods for stochastic biochemical systems

Parameters

Transcription processes

 

ML

DFD-CDF

DFD-PDF

Bounds

True value

k 1f

0.4061

0.4082

0.4292

[0,5]

0.42

k 1b

0.211

0.1171

0.8296

[0,5]

0.2485

k 2f

74.1848

25.9882

99.7701

[0,100]

50

k 2b

4.1423

18.8779

2.0815

[0,20]

10

k 3f

3.2 × 10-3

3.87 × 10-3

0.0166

[0,5]

3.032 × 10-3

k 3b

17.2405

19.9408

19.7665

[0,20]

10

α

0.1

0.0183

0.0211

[0,5]

0.025

Irreversible processes

κ R

0.8939

0.9296

0.8078

[0,5]

1

κ P

2.0345

1.1103

1.0995

[0,5]

1

γ R

7.3543

5.2431

5.4116

[0,10]

5

γ P

0.0116

0.0124

0.012

[0,5]

0.0125

κ R t

0.4376

0.4157

0.4152

[0,5]

0.417

κ P t

1.7641

0.9755

1.3732

[0,5]

1

γ R t

4.3235

2.9034

3.9315

[0,10]

3

γ P t

0.0107

0.0116

0.0103

[0,5]

0.0125