Skip to main content
Figure 5 | BMC Bioinformatics

Figure 5

From: PeakAnalyzer: Genome-wide annotation of chromatin binding and modification loci

Figure 5

Distribution of the central positions of individual transcription factor binding sites located within gene components. Using the NDG function of PeakAnnotator, the percentage of transcription factor-binding sites falling within specific gene components was calculated. As illustrated here, some factors have a clear preference for promoters and regions of transcription initiation, while others exhibit a shift in binding-site occupancy from 5' regions to introns. Interestingly, the fraction of binding sites in last introns and 3' UTRs remain relatively constant among transcription factor-binding profiles, while the widest variation in within-gene composition occurs in the number of binding sites present in higher rank-order introns.

Back to article page