Figure 5From: PeakAnalyzer: Genome-wide annotation of chromatin binding and modification lociDistribution of the central positions of individual transcription factor binding sites located within gene components. Using the NDG function of PeakAnnotator, the percentage of transcription factor-binding sites falling within specific gene components was calculated. As illustrated here, some factors have a clear preference for promoters and regions of transcription initiation, while others exhibit a shift in binding-site occupancy from 5' regions to introns. Interestingly, the fraction of binding sites in last introns and 3' UTRs remain relatively constant among transcription factor-binding profiles, while the widest variation in within-gene composition occurs in the number of binding sites present in higher rank-order introns.Back to article page