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Table 1 Power for the Survival Dimensionality Reduction (SDR) algorithm in models with cumulative prevalence K(tn) = 0.750

From: Survival dimensionality reduction (SDR): development and clinical application of an innovative approach to detect epistasis in presence of right-censored data

  

H2(t5)

Model

RCR

0.10

0.15

0.20

0.25

UBT

50%

52

81

95

97

 

70%

59

73

93

93

DFR

50%

52

87

97

98

 

70%

48

77

87

96

IFR

50%

51

88

92

99

 

70%

50

87

91

98

BT

50%

46

74

93

97

 

70%

43

72

91

95

EXP

50%

50

82

95

99

 

70%

47

80

90

96

  1. Power of the SDR algorithm in simulated datasets modelled using the 5 classes of survival distribution described by the logistic-exponential equation. Different degrees of right-censoring rate (RCR), and cumulative heritability at the survival time [H2(t5)] are considered. UBT, upside-down bathtub-shaped failure rate; DFR, decreasing failure rate; IFR, increasing failure rate; BT bathtub-shaped failure rate; EXP, exponential.