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Table 1 Power for the Survival Dimensionality Reduction (SDR) algorithm in models with cumulative prevalence K(tn) = 0.750

From: Survival dimensionality reduction (SDR): development and clinical application of an innovative approach to detect epistasis in presence of right-censored data

   H2(t5)
Model RCR 0.10 0.15 0.20 0.25
UBT 50% 52 81 95 97
  70% 59 73 93 93
DFR 50% 52 87 97 98
  70% 48 77 87 96
IFR 50% 51 88 92 99
  70% 50 87 91 98
BT 50% 46 74 93 97
  70% 43 72 91 95
EXP 50% 50 82 95 99
  70% 47 80 90 96
  1. Power of the SDR algorithm in simulated datasets modelled using the 5 classes of survival distribution described by the logistic-exponential equation. Different degrees of right-censoring rate (RCR), and cumulative heritability at the survival time [H2(t5)] are considered. UBT, upside-down bathtub-shaped failure rate; DFR, decreasing failure rate; IFR, increasing failure rate; BT bathtub-shaped failure rate; EXP, exponential.