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Table 2 Survival dimensionality reduction (SDR) model for the rheumatoid arthritis (RA) dataset.

From: Survival dimensionality reduction (SDR): development and clinical application of an innovative approach to detect epistasis in presence of right-censored data

n-way SNPs (genes) in each dimension Training Testing p
1 rs2327832 (TNFAIP3, OLIG3) 0.263 0.2366 -
2 rs1801274 (FcγRIIa), rs10954213 (IRF5) 0.2339 0.2354 <0.05
3 rs1801274 (FcγRIIa), rs10954213 (IRF5), rs3761847 (TRAF1) 0.2219 0.2393 -
  1. Selection of the best combination of attributes by the SDR method. The model with the minimum testing IBS value in the cross-validated testing sets is indicated in boldface type. p values associated with the log-rank test statistic calculated by the 100-fold permutation test. SNP, single nucleotide polymorphism.