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Table 2 Survival dimensionality reduction (SDR) model for the rheumatoid arthritis (RA) dataset.

From: Survival dimensionality reduction (SDR): development and clinical application of an innovative approach to detect epistasis in presence of right-censored data

  

IBS

 

n-way

SNPs (genes) in each dimension

Training

Testing

p

1

rs2327832 (TNFAIP3, OLIG3)

0.263

0.2366

-

2

rs1801274 (FcγRIIa), rs10954213 (IRF5)

0.2339

0.2354

<0.05

3

rs1801274 (FcγRIIa), rs10954213 (IRF5), rs3761847 (TRAF1)

0.2219

0.2393

-

  1. Selection of the best combination of attributes by the SDR method. The model with the minimum testing IBS value in the cross-validated testing sets is indicated in boldface type. p values associated with the log-rank test statistic calculated by the 100-fold permutation test. SNP, single nucleotide polymorphism.
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BMC Bioinformatics

ISSN: 1471-2105

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