Applying unmixing to gene expression data for tumor phylogeny inference

BMC Bioinformatics

Table 1 Mixture fractions averaged by tumor type for a four component inference.

	Comp. 1	Comp. 2	Comp. 3	Comp. 4
Normal	0.5387	0.1165	0.0451	0.2998
Adenocarcinoma	0.3943	0.1196	0.1708	0.3153
Small cell (cell lines)	0.4074	0.1701	0.3493	0.0732
Small cell (primary)	0.5015	0.0952	0.2665	0.1368
Carcinoid	0.3431	0.4198	0.1304	0.1066
Large cell neuroendocrine	0.4674	0.1227	0.2093	0.2007
Large cell carcinoma	0.4010	0.0836	0.1861	0.3293
Combined SCLC/AD	0.0650	0.1586	0.4120	0.3643

Columns correspond to mixture components from a four-component inference. Rows correspond to distinct tumor types, as annotated by Jones et al. [[33]].

ISSN: 1471-2105