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Figure 5 | BMC Bioinformatics

Figure 5

From: rSW-seq: Algorithm for detection of copy number alterations in deep sequencing data

Figure 5

Simulation tests on rSW-seq and SegSeq. Different sizes (10 kb to 1 Mb) of single copy gains and losses were simulated on human chromosome 1. A hundred test chromosomes were simulated at varying sequencing depths (1 to 20 million reads). The sensitivity in detecting simulated alterations by rSW-seq is shown for single copy gain (A) and loss (B). The same simulation sequencing data was also analyzed by SegSeq, which show similar sensitivity in detecting copy number gain (C) and loss (D). The precision levels are shown for rSW-seq and SegSeq in (E).

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