Figure 4
From: Coherent pipeline for biomarker discovery using mass spectrometry and bioinformatics
Overlap and concordance between database search algorithms. Both diagrams show the intersection between the three algorithms in peptide identification. The diagram on the left shows the intersection of the algorithms at identifying peptides prior to in silico validation (first step in the pipeline). The diagram on the right shows the overlap of the different algorithms in biomarker discovery after the complete implementation of the pipeline. The arrow represents the flow of the pipeline to achieve a final refined list of biomarkers.