Figure 3

Proportion of non-differentially expressed genes as function of the fraction filtered out x ≡ 1 - γ. Each curve represents the mean of π₀(x) over 1000 simulated datasets (error bars are small but not displayed for clarity). From bottom to top, curves represent the following situations: best filter (thin solid line), fold change filter (solid line, ○), signal filter (dashed-and-dotted line, ×), variance filter (dashed line, Δ) and the random filter (thin solid line).