Skip to main content

Table 2 Clusters of structurally similar proteins.

From: Bayesian statistical modelling of human protein interaction network incorporating protein disorder information

Cluster

Size

Degrees

GO Terms enriched (Molecular Function, "MF")

Cluster 1

16

22-56

GO:0000739 DNA strand annealing activity

   

GO:0003682 chromatin binding

   

GO:0003746 translation elongation factor activity

   

GO:0004145 diamine N-acetyltransferase activity

   

GO:0004157 dihydropyrimidinase

   

GO:0004864 protein phosphatase inhibitor activity

   

GO:0016455 RNA polymerase II transcription mediator activity

   

GO:0018024 histone-lysine N-methyltransferase activity

   

GO:0050681 androgen receptor binding

Cluster 2

32

8-20

GO:0008270 zinc ion binding

Cluster 3

86

4-7

GO:0003899 DNA-directed RNA polymerase activity

   

GO:0005125 cytokine activity

   

GO:0019900 kinase binding

   

GO:0042562 hormone binding

Cluster 4

131

2-3

GO:0003777 microtubule motor activity

   

GO:0005088 Ras guanyl-nucleotide exchange factor activity

Cluster 5

136

1

GO:0003700 transcription factor activity

   

GO:0003723 RNA binding

   

GO:0003779 actin binding

   

GO:0005198 structural molecule activity

  1. Table 2 presents the groups of proteins obtained by clustering the respective sociality parameters. The number of proteins in each cluster, their degrees and molecular functions found by GO-significance analysis are displayed.
Back to article page