Table 3 Top 50 single-substitution patterns 2-5 bp sorted by context bias
From: Context dependent substitution biases vary within the human genome
Pattern | Context bias | 95% Conf. Int. | Rel. abund. | 95% Conf. Int. |
|---|---|---|---|---|
1. CG→TG (CG→CA) | 2.926e-03 | 2.907e-03 - 2.945e-03 | 7.5809 | 7.5581 - 7.6049 |
2. AT→GT (AT→AC) | 2.148e-04 | 2.125e-04 - 2.173e-04 | 1.5444 | 1.5401 - 1.5492 |
3. TG→CG (CA→CG) | 1.372e-04 | 1.351e-04 - 1.392e-04 | 1.3861 | 1.3816 - 1.3906 |
4. TG→TA (CA→TA) | -1.025e-04 | -1.021e-04 - -1.029e-04 | 0.6367 | 0.6341 - 0.6391 |
5. CT→TT (AG→AA) | -9.985e-05 | -9.947e-05 - -1.002e-04 | 0.6136 | 0.6110 - 0.6161 |
6. TNG→CNG (CNA→CNG) | 7.681e-05 | 7.571e-05 - 7.790e-05 | 1.5309 | 1.5252 - 1.5365 |
7. TT→TC (AA→GA) | -7.532e-05 | -7.497e-05 - -7.568e-05 | 0.6385 | 0.6355 - 0.6413 |
8. GT→AT (AC→AT) | 6.859e-05 | 6.691e-05 - 7.038e-05 | 1.1903 | 1.1868 - 1.1943 |
9. TC→TT (GA→AA) | -6.753e-05 | -6.697e-05 - -6.808e-05 | 0.7425 | 0.7399 - 0.7454 |
10. GG→GA (CC→TC) | -6.618e-05 | -6.573e-05 - -6.664e-05 | 0.7081 | 0.7049 - 0.7114 |
11. TT→CT (AA→AG) | -5.828e-05 | -5.770e-05 - -5.884e-05 | 0.7672 | 0.7641 - 0.7703 |
12. TC→CC (GA→GG) | -4.745e-05 | -4.718e-05 - -4.771e-05 | 0.6333 | 0.6296 - 0.6370 |
13. CG→CT (CG→AG) | 3.809e-05 | 3.676e-05 - 3.950e-05 | 2.2765 | 2.2495 - 2.3054 |
14. CT→CC (AG→GG) | -3.210e-05 | -3.144e-05 - -3.275e-05 | 0.8438 | 0.8402 - 0.8479 |
15. GNG→ANG (CNC→CNT) | 2.937e-05 | 2.857e-05 - 3.014e-05 | 1.1720 | 1.1682 - 1.1759 |
16. CG→GG (CG→CC) | 2.462e-05 | 2.358e-05 - 2.564e-05 | 1.9887 | 1.9605 - 2.0182 |
17. AT→TT (AT→AA) | 2.382e-05 | 2.294e-05 - 2.468e-05 | 1.3335 | 1.3244 - 1.3433 |
18. TA→TG (TA→CA) | 2.340e-05 | 2.218e-05 - 2.455e-05 | 1.0990 | 1.0942 - 1.1039 |
19. TNA→TNG (TNA→CNA) | -2.243e-05 | -2.214e-05 - -2.270e-05 | 0.7903 | 0.7866 - 0.7938 |
20. GG→AG (CC→CT) | 2.236e-05 | 2.105e-05 - 2.373e-05 | 1.0655 | 1.0620 - 1.0692 |
21. GNG→GNA (CNC→TNC) | 1.910e-05 | 1.839e-05 - 1.976e-05 | 1.1173 | 1.1134 - 1.1217 |
22. TNG→TNA (CNA→TNA) | -1.873e-05 | -1.833e-05 - -1.913e-05 | 0.8679 | 0.8648 - 0.8713 |
23. TNT→CNT (ANA→ANG) | -1.844e-05 | -1.802e-05 - -1.887e-05 | 0.8750 | 0.8715 - 0.8783 |
24. CNT→CNC (ANG→GNG) | 1.733e-05 | 1.670e-05 - 1.801e-05 | 1.1524 | 1.1478 - 1.1575 |
25. TG→TC (CA→GA) | -1.692e-05 | -1.660e-05 - -1.721e-05 | 0.7668 | 0.7612 - 0.7723 |
26. GNT→ANT (ANC→ANT) | -1.673e-05 | -1.630e-05 - -1.714e-05 | 0.8848 | 0.8814 - 0.8884 |
27. GT→TT (AC→AA) | 1.630e-05 | 1.552e-05 - 1.709e-05 | 1.2006 | 1.1920 - 1.2093 |
28. TG→GG (CA→CC) | 1.610e-05 | 1.530e-05 - 1.682e-05 | 1.2087 | 1.1999 - 1.2166 |
29. CT→AT (AG→AT) | -1.535e-05 | -1.500e-05 - -1.568e-05 | 0.7949 | 0.7894 - 0.8006 |
30. TGG→CGG (CCA→CCG) | -1.482e-05 | -1.468e-05 - -1.496e-05 | 0.7151 | 0.7116 - 0.7185 |
31. TA→TT (TA→AA) | 1.343e-05 | 1.273e-05 - 1.411e-05 | 1.2402 | 1.2297 - 1.2504 |
32. TC→TA (GA→TA) | -1.182e-05 | -1.149e-05 - -1.214e-05 | 0.8167 | 0.8109 - 0.8236 |
33. GNT→TNT (ANC→ANA) | 1.175e-05 | 1.135e-05 - 1.223e-05 | 1.2551 | 1.2474 - 1.2636 |
34. TTG→CTG (CAA→CAG) | 1.173e-05 | 1.136e-05 - 1.208e-05 | 1.2408 | 1.2347 - 1.2469 |
35. TT→AT (AA→AT) | -1.172e-05 | -1.147e-05 - -1.200e-05 | 0.7803 | 0.7727 - 0.7868 |
36. TC→TG (GA→CA) | 1.163e-05 | 1.093e-05 - 1.239e-05 | 1.1358 | 1.1279 - 1.1433 |
37. TNC→TNT (GNA→ANA) | -1.152e-05 | -1.099e-05 - -1.204e-05 | 0.9305 | 0.9273 - 0.9337 |
38. GT→GC (AC→GC) | 1.090e-05 | 9.893e-06 - 1.202e-05 | 1.0588 | 1.0539 - 1.0639 |
39. TT→TG (AA→CA) | 1.033e-05 | 9.639e-06 - 1.105e-05 | 1.1141 | 1.1073 - 1.1212 |
40. GGC→GGT (GCC→ACC) | 9.916e-06 | 9.571e-06 - 1.026e-05 | 1.2075 | 1.2018 - 1.2140 |
41. GC→GG (GC→CC) | -9.655e-06 | -9.383e-06 - -9.932e-06 | 0.7853 | 0.7772 - 0.7938 |
42. CT→GT (AG→AC) | 9.557e-06 | 8.870e-06 - 1.027e-05 | 1.0969 | 1.0904 - 1.1033 |
43. TT→TA (AA→TA) | -9.479e-06 | -9.164e-06 - -9.822e-06 | 0.8338 | 0.8268 - 0.8413 |
44. TC→GC (GA→GC) | -9.314e-06 | -9.093e-06 - -9.545e-06 | 0.7587 | 0.7509 - 0.7677 |
45. GNG→CNG (CNC→CNG) | 9.304e-06 | 8.933e-06 - 9.707e-06 | 1.2409 | 1.2320 - 1.2497 |
46. GNNG→GNNA (CNNC→TNNC) | 9.232e-06 | 8.864e-06 - 9.596e-06 | 1.1145 | 1.1104 - 1.1185 |
47. GG→TG (CC→CA) | -8.903e-06 | -8.530e-06 - -9.274e-06 | 0.8544 | 0.8467 - 0.8619 |
48. TNNG→TNNA (CNNA→TNNA) | -8.708e-06 | -8.482e-06 - -8.924e-06 | 0.8822 | 0.8787 - 0.8856 |
49. TG→TT (CA→AA) | -8.545e-06 | -8.105e-06 - -9.015e-06 | 0.9046 | 0.8987 - 0.9102 |
50. GG→CG (CC→CG) | -7.914e-06 | -7.543e-06 - -8.279e-06 | 0.8664 | 0.8596 - 0.8745 |