Parallel multiplicity and error discovery rate (EDR) in microarray experiments

BMC Bioinformatics

Table 2 EDR calculation

id	Gene	raw-p	x _i	f _i	N'	EDR
M72885_rna1_s_at	GOS2	0.00018432	309.453094	5.318301	2	0.00000028
X15729_s_at	DDX5	0.00044674	2.773653	1.332583	4	0.00193717
M34516_r_at	IGL@	0.00321646	10.316779	1.807361	27	0.01042631
D11428_at	PMP22	0.00342428	20.312435	1.910159	30	0.00555663
HG3514-HT3708_at	Tropomyosin	0.00437053	41.545886	1.188196	33	0.01844629
L20971_at	PDE4B	0.00494670	3.348770	1.998387	42	0.06214142
U33448_s_at	LTB4R	0.00625588	0.582200	1.066264	53	1

EDR detection of the Hyperinsulinemic data set. The EDR of gene i is the expectation of raw-p of this gene (p_i) multiplied by the number of negative gene controls (N') at p- value equal to or greater than 1- p_i, divided by the ratio of the maximum group mean of this gene with the median value of all genes (x_i) and by the fold changes (f_i) minus 1.

ISSN: 1471-2105