Figure 3From: Investigating the validity of current network analysis on static conglomerate networks by protein network stratificationHub/Bottleneck status change between the total network and stratified Subnetworks. Each circle represents a PPI network. 20% was used as the cutoff for hub/bottleneck definition. P-values were calculated by Student's t-tests comparing percentages of hub/bottleneck status change of real networks with those of randomized networks of similar size and degree distribution. The results are generally consistent when using 5% or 10% as cutoffs for hub/bottleneck definitions [Table S3, S4 in Additional file 2].Back to article page