Figure 8

Differentially expressed genes mapped on the pathway ontology. Color indicates the ratio of up/down regulated genes; height shows the log value of total number of differentially expressed genes. Most of the upper side of ontology categories is down-regulated, while some categories on the lower-left side are up-regulated. Zoomed in view (center) shows the detail of amino acids biosynthesis. (bottom) shows that two superpathways (histidine, purine, and pyrimidine biosynthesis, and chorismate) have many more genes differentially expressed downward than other superpathways.