Figure 5

Phylogenetic profile differences. This figure presents the phylogenetic profile differences found for the random graphs generated based on the 3 different empirical datasets in comparison to those found in the original graph. The red points show the proportion found in the empirical PIN dataset, whilst the boxplots present the data from the random graphs. The empirical data, shown as red dots for each boxplot, are generally higher for differences less than 4, showing that the observed PPIs are more likely to share phylogenetic profiles than those edges found in any of the random graph ensembles.