Figure 2

The network (N1) of the significantly differentially expressed genes from the leukemia data set, where the similarity between the chosen genes was calculated based on their co-membership in biological pathways. Only components with at least two vertices (similarity threshold equal to 0.7) are included in the network. Genes represented with solid circles were significantly over-expressed in the ALL samples and genes shown as empty circles had higher expression in the AML samples. The individual components are named according to the prevailing Gene Ontology annotation. Components were grouped and labeled manually by the expert.