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Table 1 Super-biclusters in gastric cancer dataset

From: A bi-ordering approach to linking gene expression with clinical annotations in gastric cancer

 

#Converging

 

P-values

 

Most significant biological process

SBC

SBC

Prototype

MCS

Malignancy Score

GO

 

SBC1

11

6

9.4 × 10-4

1.8 × 10-13

5.1 × 10-9

epidermis development

SBC2

188

7

1.0 × 10-8

 

7.1 × 10-7

lipid metabolic process

SBC3

2

1

1.5 × 10-6

5.5 × 10-8

3.2 × 10-32

immune system process

SBC4

96

2

1.8 × 10-1

 

2.0 × 10-53

immune system process

SBC5

15

15

1.1 × 10-18

7.7 × 10-21

1.8 × 10-14

cell cycle process

SBC6

328

11

3.0 × 10-7

4.9 × 10-8

1.8 × 10-20

multicellular organismal process

SBC7

359

229

4.0 × 10-14

-5.4 × 10-22

3.2 × 10-22

gen. of precursor metabolic & energy

SBC8

1

1

3.0 × 10-10

-5.2 × 10-8

2.2 × 10-2

lipid metabolic process

  1. Numerical characterisations and biological relevance of the eight super-biclusters generated by BOA on the gastric cancer data. In the second column of the table, the numbers of biclusters that converged to a particular super-bicluster are given, while the third column is the number of identical biclusters converging to the prototype of that super-bicluster. The columns of "MCS", "Malignancy Score" and "GO" contain the p-values calculated with respect to the prototype of each super-bicluster in terms of the three statistics described in Section 2.3. Note that the negative sign, '-', in the Malignancy Score for SBC7 and SBC8 indicates the significance of agreement with the reverse order.