Figure 5
From: An integrated analysis of molecular aberrations in NCI-60 cell lines
Trans acting effects of DNA methylations on gene expressions. Left: DNA methylation and gene expression data of the top 2 clusters of external methylation associations. From the top, the heatmap of the rows displays (1)methylation data of 16 genes in cluster 1, the height of each pixel is amplified ten times, (2)expression data of 490 genes associated with the methylated genes in cluster 1, (3)a black separator of the two clusters, (4)methylation data of 2 genes in cluster 2, the height of each pixel is amplified ten times, (5)expression data of 157 genes associated with the methylated genes in cluster 2. Right: DNA methylation and gene expression data pertaining to 3 PAX genes. From the top, the heatmap displays (1)PAX3 methylation data, (2)expression data of 115 genes associated with PAX3 methylation, (3)a black separator, (4)PAX7 methylation data, (5)expression data of 140 genes associated with PAX7 methylation, (6)a black separator, (7)PAX8 methylation data, (8)expression data of 83 genes associated with PAX8 methylation. Tissue abbreviations: BR:breast, CNS:central nervous system, CO:colon, LE:leukemia, ME:melanoma, LC:lung, OV:ovarian, KD:kidney.