From: An integrated analysis of molecular aberrations in NCI-60 cell lines
layer | aberration | # explained genes validation | |
---|---|---|---|
1 | internal CNV | 37 | coverage 31.9% (37 of 116) |
1 | internal mutation | 3 | coverage 50% (3 of 6) |
1 | internal methylation | 15 | coverage 7.98% (15 of 188) |
1 | internal mRNA | 46 | coverage 68% (46 of 68) |
2 | internal segment CNV | 2165 | coverage 26.77% (2165 of 8067) |
2 | transcription factor | 6 | coverage 3.87% (6 of 155) |
3 | external segment CNV | 1547 | 3 TFs examined, 2 verified |
3 | external mutation | 392 | 1 TF examined and verified |
3 | external methylation | 935 | 7 TFs examined, 1 verified |