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Table 1 Annotations enriched in differentially coexpressed modules

From: DiffCoEx: a simple and sensitive method to find differentially coexpressed gene modules

Module Category Subcategory Expected Observed fdr
Black KEGG Metabolism of xenobiotics by cytochrome P450 1.367 12 <0.001
KEGG Metabolic pathways 22.494 40 <0.001
GO Glutathione transferase activity 0.364 9 <0.001
Blue KEGG Lysosome 3.373 12 0.008
KEGG Metabolic pathways 31.541 48 0.026
GO Mitochondrion 35.764 67 <0.001
Brown GO Intracellular transport 8.481 22 0.038
Green GO Mitochondrion 10.234 26 0.003
GO Oxidation reduction 4.015 15 0.003
Orange GO Xenobiotic metabolic process 0.079 5 <0.001
Purple No significant enrichment
Red KEGG Endometrial cancer 0.201 3 0.015
Yellow KEGG Pancreatic cancer 3.344 14 <0.001
KEGG Renal cell carcinoma 3.702 10 0.043
KEGG Pathways in cancer 14.75 27 0.022
GO Protein localization 33.676 64 <0.001
GO Melanosome 2.995 11 0.009
GO Cell projection 33.886 59 0.002
GO Small GTPase mediated signal transduction 14.342 31 0.003
  1. Selected annotations enriched among the genes of each differentially coexpressed modules and associated false discovery rates (fdr). The over-representation analysis was conducted using GeneTrail. The complete results are available in Additional File 3.