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Figure 8 | BMC Bioinformatics

Figure 8

From: Challenges in microarray class discovery: a comprehensive examination of normalization, gene selection and clustering

Figure 8

Normalization. Boxplots showing the performance (adjusted Rand) for the normalizations. The plot shows the distributions of aRand values for the data sets separately. supervised gene selection, selecting 100 genes using the methods Mdiff and T2. The distributions represented by the boxplots are based on 72 cluster analysis for each normalization.gene selections). The cluster analyses consist of combinations of the following sub-processes: standardization and not standardization; missing value imputation by ROW and SVD; gene selections NONE, STD 100, STD 1000 and PC 15; clustering methods hclust.corr.ward, hclust.eucl.ward, hclust.manh.ward, kmeans and Mclust (for 100 genes or less). The horizontal lines show the median (dashed line) and 95-percentile (dotted line) for the distribution of aRand values for random classifications.

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