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Table 19 Complexes derived with lesser accuracy or missed by MCL-CAw due to affinity scoring

From: MCL-CAw: a refinement of MCL for detecting yeast complexes from weighted PPI networks by incorporating core-attachment structure

Matched benchmark complex #Proteins in complexes from #Incorrect proteins in complexes from ICD(G+K) Accuracies (Jaccard scores)
Name #Proteins G+K ICD(G+K) Missed Addnl G+K ICD(G+K)
Kornbergs SRB 25 24 23 2 0 0.960 0.920
SWI/SNF 12 11 8 4 0 0.769 0.667
TRAPP 10 10 9 1 0 1.000 0.900
19/22 S reg 22 20 27 0 5 0.909 0.815
TRAMP 3 4 7 0 4 0.750 0.429
Alpha-1,6 5 9 11 0 6 0.556 0.455
eIF3 7 8 14 1 8 0.500 0.400
Protein phosp 3 5 9 0 4 0.600 0.333
Cdc73p/Paf1p 7 7 18 0 11 0.556 0.388
Chs5p/Arf-1 6 8 10 2 6 0.556 0.400
  1. The upper half shows sample complexes from Wodak lab derived with lower accuracies from the ICD(Gavin+Krogan) network compared to those from the Gavin+Krogan network. The lower half shows those missed from the ICD(Gavin+Krogan) network. The #Incorrect proteins in ICD(Gavin+Krogan) network is with respect to the benchmark complexes.