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Table 20 Essential genes in the predicted complexes of MCL-CAw

From: MCL-CAw: a refinement of MCL for detecting yeast complexes from weighted PPI networks by incorporating core-attachment structure

  Number (Proportion) of Essential genes present in
PPI Network Whole network Predicted cores Predicted complexes Matched predictions
ICD(Gavin+Krogan) 604 (0.537) 510 (0.454) 552 (0.491) 469 (0.417)
FSW(Gavin+Krogan) 604 (0.537) 510 (0.454) 552 (0.491) 470 (0.418)
Consolidated3.19 611 (0.544) 568 (0.506) 576 (0.513) 497 (0.442)
Bootstrap0.094 757 (0.674) 634 (0.564) 676 (0.601) 578 (0.514)
  1. The figures in brackets represent the proportion of essential genes present in the corresponding group out of the 1123 total essential genes obtained from the Yeast Genome Deletion project [36, 37].
  2. # Essential genes in YDP: 1123