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Table 20 Essential genes in the predicted complexes of MCL-CAw

From: MCL-CAw: a refinement of MCL for detecting yeast complexes from weighted PPI networks by incorporating core-attachment structure

 

Number (Proportion) of Essential genes present in

PPI Network

Whole network

Predicted cores

Predicted complexes

Matched predictions

ICD(Gavin+Krogan)

604 (0.537)

510 (0.454)

552 (0.491)

469 (0.417)

FSW(Gavin+Krogan)

604 (0.537)

510 (0.454)

552 (0.491)

470 (0.418)

Consolidated3.19

611 (0.544)

568 (0.506)

576 (0.513)

497 (0.442)

Bootstrap0.094

757 (0.674)

634 (0.564)

676 (0.601)

578 (0.514)

  1. The figures in brackets represent the proportion of essential genes present in the corresponding group out of the 1123 total essential genes obtained from the Yeast Genome Deletion project [36, 37].
  2. # Essential genes in YDP: 1123