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Table 1 Statistics of the tested PPI networks.

From: Examination of the relationship between essential genes in PPI network and hub proteins in reverse nearest neighbor topology

Organism

PPI network name

Number of proteins

Number of interactions

Average degree

Number (Proportion) of essential proteins

E Coli

DIP Core

1,223

993

1.62

113 (0.09)

Yeast

DIP Core

3,645

4,553

2.50

690 (0.19)

 

Krogan

2,674

7,079

5.29

712 (0.27)

 

Gavin

1,430

7,592

10.62

576 (0.40)

 

Collins

1,958

23,486

23.99

622 (0.31)

 

HC

2,998

9,258

6.18

871 (0.29)

  1. Proportion of essential proteins was computed as the number of essential proteins, divided by the total number of proteins in the PPI network.