Figure 4
From: Confronting two-pair primer design for enzyme-free SNP genotyping based on a genetic algorithm
An example of a crossover operation for CTPP primer design. First, randomly select two P v from the population, for example Pv 1= (25, 118, 23, 24, 256, 25) and Pv 2= (23, 212, 26, 25, 119, 22). Then randomly generate a mask of 6 binary bits i.e., 011001, and based on this mask, exchange the value of Pl 1, Rl 1and Rl 2. Finally, the new offsprings P'v 1= (25, 212, 26, 24, 256, 22) and P'v 2= (23, 118, 23, 25, 119, 25) are generated.