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Table 4 Connecting CS transcriptional modules to enriched gene ontology terms (p-value < 0.0001)

From: Comparative analysis of acute and chronic corticosteroid pharmacogenomic effects in rat liver: Transcriptional dynamics and regulatory structures

No. Gene Ontology Terms* Module 1 Module 2 Module 3 Module 4 Module 5 Module 6
1 Metabolic process Amino acid, compound, organic acid X      
   mRNA   X     
   Nucleotide, nucleoside    X    
   Protein, macromolecule     X   X
2 Binding Cofactor, coenzyme, vitamin, heme, ion X      
   Nucleotide, nucleic acid binding   X     
   RNA binding       X
   Protein binding     X   X
3 Cellular catabolic process X      
4 Catalytic, oxidoreductase activity X   X    
5 Oxidative phosphorylation    X    
6 Transmembrane transporter activity    X    
7 Protein-RNA complex assembly   X     
8 RNA splicing, processing   X     
9 Gene expression   X   X   X
10 Translation activity   X   X   
11 Biosynthetic process     X   
12 Structural molecule activity     X   
  1. *: Details are listed in functional characterization in Additional File 3.