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Table 4 Connecting CS transcriptional modules to enriched gene ontology terms (p-value < 0.0001)

From: Comparative analysis of acute and chronic corticosteroid pharmacogenomic effects in rat liver: Transcriptional dynamics and regulatory structures

No.

Gene Ontology Terms*

Module 1

Module 2

Module 3

Module 4

Module 5

Module 6

1

Metabolic process

Amino acid, compound, organic acid

X

     
  

mRNA

 

X

    
  

Nucleotide, nucleoside

  

X

   
  

Protein, macromolecule

   

X

 

X

2

Binding

Cofactor, coenzyme, vitamin, heme, ion

X

     
  

Nucleotide, nucleic acid binding

 

X

    
  

RNA binding

     

X

  

Protein binding

   

X

 

X

3

Cellular catabolic process

X

     

4

Catalytic, oxidoreductase activity

X

 

X

   

5

Oxidative phosphorylation

  

X

   

6

Transmembrane transporter activity

  

X

   

7

Protein-RNA complex assembly

 

X

    

8

RNA splicing, processing

 

X

    

9

Gene expression

 

X

 

X

 

X

10

Translation activity

 

X

 

X

  

11

Biosynthetic process

   

X

  

12

Structural molecule activity

   

X

  
  1. *: Details are listed in functional characterization in Additional File 3.
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BMC Bioinformatics

ISSN: 1471-2105

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