Figure 1From: Sites Inferred by Metabolic Background Assertion Labeling (SIMBAL): adapting the Partial Phylogenetic Profiling algorithm to scan sequences for signatures that predict protein functionThe phylogenetic distribution of urea metabolism in bacteria is broad and sporadic. The urease system (GenProp0051, blue circles) and the urea carboxylase/allophanate hydrolase pathway (GenProp0481, green circles) are plotted on the AMPHORA inferred phylogenetic tree of prokaryotes from Eisen & Wu[24]. Certain archaeal species also metabolize urea and are not shown (although they were included in the analyses).Back to article page