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Figure 5 | BMC Bioinformatics

Figure 5

From: Sites Inferred by Metabolic Background Assertion Labeling (SIMBAL): adapting the Partial Phylogenetic Profiling algorithm to scan sequences for signatures that predict protein function

Figure 5

Structural mapping of UrtBC SIMBAL hotspots. Left: Mapping onto the "inward-open" structure of HI1471 [PDB:2NQ2][13]. Right: Mapping onto the "outward-open" structure of BtuC [PDB:1L7V][12]. SIMBAL hotspots are clustered around the inward-facing pore. In each example the homodimeric structures are shown in blue and green, with one subunit (blue) representing UrtB, and the other (green) representing UrtC. Hotspots are shown in red and orange, respectively. Molecular models visualized with MacPyMOL http://www.pymol.org/.

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BMC Bioinformatics

ISSN: 1471-2105

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