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Figure 6 | BMC Bioinformatics

Figure 6

From: Sites Inferred by Metabolic Background Assertion Labeling (SIMBAL): adapting the Partial Phylogenetic Profiling algorithm to scan sequences for signatures that predict protein function

Figure 6

SIMBAL results on PrmC RF-1-specific methylases versus a PrmC/RF-1 proximity partition of the TIGR00536 PrmC-like methylase family. A) SIMBAL triangle heat map for the Bordetella bronchiseptica RB50 PrmC protein (BB0385, [GenBank:CAE30883]). B) A SIMBAL score plot of 10 PrmC proteins averaged after local registration of the SIMBAL hotspots by alignment of the corresponding subsequences, at a window size of 14 (blue) and, in the vicinity of peak E, at 6 amino acids (black). The average SIMBAL score for the full-length proteins is shown in red. PrmC sequences came from the genomes of: E. coli 536, Arthrobacter aurescans, Bacillus clausii KSM-K16, Mycoplasma hyopneumoniae 232, Mesoplasma florum, Sinorhizobium meliloti 1021, Zymomonas mobilis ZM4, Rhodococcus sp. RHA1, Desulfitobacterium hafniense Y51 and Bordatella bronchiseptica RB50.

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