|
Gene
|
Chr
|
Start
|
End_pos
|
SNPs/rvSNPs
|
QT+RV
|
QT-RV
|
QT+RV mean
|
QT-RV mean
|
p-val
|
BetaCoef
|
St.Er
|
[lowCI - upCI]
|
t-test
|
t-test_p-val
|
|---|
|
MIB2
|
1
|
0
|
107622
|
(10/1)
|
106
|
1125
|
-0.367
|
0.037
|
6.77E-05
|
0.404
|
0.101
|
[0.206 - 0.602]
|
-3.975
|
3.72E-05
|
|
GOLGA8C
|
15
|
18977714
|
19091040
|
(29/4)
|
127
|
1097
|
-0.347
|
0.042
|
3.19E-05
|
0.389
|
0.093
|
[0.206 - 0.571]
|
-4.149
|
1.78E-05
|
|
TPO
|
2
|
1346242
|
1575502
|
(29/6)
|
70
|
1158
|
0.478
|
-0.028
|
4.00E-05
|
-0.506
|
0.122
|
[-0.746 - -0.266]
|
4.107
|
1.80E-05
|
|
EXOC3
|
5
|
446375
|
570407
|
(24/1)
|
4
|
1228
|
1.935
|
-0.006
|
1.00E-04
|
-1.941
|
0.498
|
[-2.918 - -0.964]
|
3.874
|
5.12E-05
|
|
C10orf110
|
10
|
1008606
|
1130138
|
(66/4)
|
111
|
1116
|
0.379
|
-0.036
|
4.00E-05
|
-0.415
|
0.099
|
[-0.609 - -0.221]
|
4.161
|
1.48E-05
|
- This file provides summary statistics for all genes that achieved a p value ≤ the p value set by the -pout command line option. The summary file is a tab-delimited file with 15 columns: Gene/Window name, Chromosome, Starting bp position, End bp position, Number of SNPs in the Gene/Window, Number of individuals with low frequency/rare variant minor alleles, Number of individuals without low frequency/rare variant minor alleles, The mean QT value of individuals with low frequency/rare variant minor alleles, The mean QT value of individuals without low frequency/rare variant minor alleles, The p value of the linear regression, The Beta coefficient from the linear regression, The Standard Error of the Beta Coefficient, the lower and upper 95% confidence intervals of Beta, The t-statistic, and The t-statistic p value.
