Skip to main content

Table 1 Properties of MDR families

From: Subdivision of the MDR superfamily of medium-chain dehydrogenases/reductases through iterative hidden Markov model refinement

ID Name Size Swiss-Prot PCID Avg (StdDev) Eukaryotic Bacterial Archaeal
MDR001 ADH 2217 116 51.24 (19.02) 1315 (59.3%) 895 (40.4%) 6 (0.3%)
MDR002 PTGR 774 17 42.46 (9.64) 253 (32.7%) 518 (66.9%) 3 (0.4%)
MDR003 FAS 706 11 39.07 (9.88) 288 (40.8%) 418 (59.2%) 0 (0.0%)
MDR004 QORX 486 1 47.47 (10.07) 69 (14.2%) 417 (85.8%) 0 (0.0%)
MDR005 PDH 328 18 45.59 (11.81) 181 (55.2%) 146 (44.5%) 1 (0.3%)
MDR006 ZADH2 56 4 51.49 (15.19) 51 (91.1%) 5 (8.9%) 0 (0.0%)
MDR007 MECR 51 9 54.60 (13.15) 51 (100.0%) 0 (0.0%) 0 (0.0%)
MDR008 VAT1 50 6 60.49 (19.60) 48 (96.0%) 2 (4.0%) 0 (0.0%)
MDR009 vertQOR 22 8 70.12 (10.34) 21 (95.5%) 1 (4.5%) 0 (0.0%)
MDR010 CAD 661 32 49.08 (10.02) 329 (49.8%) 330 (49.9%) 2 (0.3%)
MDR011 bpQOR 575 5 47.93 (11.86) 66 (11.5%) 509 (88.5%) 0 (0.0%)
MDR012 YHDH 481 2 53.92 (11.43) 1 (0.2%) 477 (99.2%) 0 (0.0%)
MDR013 FDH 375 4 47.16 (12.56) 29 (7.7%) 346 (92.3%) 0 (0.0%)
MDR014 TDH 351 126 69.40 (16.11) 1 (0.3%) 343 (97.7%) 7 (2.0%)
MDR015 QORL2 319 4 45.25 (8.76) 38 (11.9%) 281 (88.1%) 0 (0.0%)
MDR016 bADH 313 17 60.72 (15.62) 1 (0.3%) 312 (99.7%) 0 (0.0%)
MDR017   279 8 51.97 (8.93) 2 (0.7%) 277 (99.3%) 0 (0.0%)
MDR018   194 1 47.22 (10.60) 48 (24.7%) 146 (75.3%) 0 (0.0%)
MDR019   136 0 60.51 (12.37) 18 (13.2%) 118 (86.8%) 0 (0.0%)
MDR020 yADH 128 22 63.56 (12.11) 128 (100.0%) 0 (0.0%) 0 (0.0%)
MDR021 YJGB 122 1 69.98 (20.96) 2 (1.6%) 120 (98.4%) 0 (0.0%)
MDR022 giFDH 122 2 63.32 (18.53) 5 (4.1%) 111 (91.0%) 6 (4.9%)
MDR023   72 5 52.93 (17.12) 10 (13.9%) 56 (77.8%) 6 (8.3%)
MDR024   40 0 52.66 (11.72) 7 (17.5%) 32 (80.0%) 1 (2.5%)
MDR025 yPDH 34 0 65.44 (13.11) 34 (100.0%) 0 (0.0%) 0 (0.0%)
MDR026 yDH 34 0 60.48 (13.13) 34 (100.0%) 0 (0.0%) 0 (0.0%)
MDR027 QORH 34 2 60.28 (10.85) 34 (100.0%) 0 (0.0%) 0 (0.0%)
MDR028   29 0 55.36 (9.11) 1 (3.4%) 28 (96.6%) 0 (0.0%)
MDR029 yADH2 29 1 59.02 (15.24) 29 (100.0%) 0 (0.0%) 0 (0.0%)
MDR030 dFAS 28 0 57.51 (16.34) 28 (100.0%) 0 (0.0%) 0 (0.0%)
MDR031 yDH2 28 0 53.43 (12.87) 28 (100.0%) 0 (0.0%) 0 (0.0%)
MDR032 bADH2 26 0 69.59 (17.08) 1 (3.8%) 25 (96.2%) 0 (0.0%)
MDR033 yBDH 23 2 54.51 (12.62) 23 (100.0%) 0 (0.0%) 0 (0.0%)
MDR034   23 0 54.57 (14.09) 13 (56.5%) 10 (43.5%) 0 (0.0%)
MDR035   22 0 47.17 (10.55) 22 (100.0%) 0 (0.0%) 0 (0.0%)
MDR036 bADH3 21 4 50.26 (15.82) 1 (4.8%) 12 (57.1%) 8 (38.1%)
MDR037   20 0 66.14 (13.09) 20 (100.0%) 0 (0.0%) 0 (0.0%)
MDR038   20 0 74.56 (12.47) 20 (100.0%) 0 (0.0%) 0 (0.0%)
MDR039 bADH4 150 0 58.99 (10.83) 0 (0.0%) 150 (100.0%) 0 (0.0%)
MDR040 SORE 117 2 61.62 (21.91) 0 (0.0%) 117 (100.0%) 0 (0.0%)
MDR041 BurkDH 114 0 63.89 (15.74) 0 (0.0%) 114 (100.0%) 0 (0.0%)
MDR042 YJJN 114 1 57.50 (18.31) 0 (0.0%) 114 (100.0%) 0 (0.0%)
MDR043 IDND 96 1 55.99 (17.90) 0 (0.0%) 96 (100.0%) 0 (0.0%)
MDR044   96 0 54.24 (13.62) 0 (0.0%) 92 (95.8%) 4 (4.2%)
MDR045   89 0 56.57 (14.09) 0 (0.0%) 89 (100.0%) 0 (0.0%)
MDR046 RSPB 78 1 72.88 (16.80) 0 (0.0%) 78 (100.0%) 0 (0.0%)
MDR047   72 0 58.49 (18.18) 0 (0.0%) 72 (100.0%) 0 (0.0%)
MDR048 GATD 71 2 83.33 (14.94) 0 (0.0%) 71 (100.0%) 0 (0.0%)
MDR049   69 0 54.89 (14.55) 0 (0.0%) 69 (100.0%) 0 (0.0%)
MDR050 CCR 67 0 72.88 (15.83) 0 (0.0%) 67 (100.0%) 0 (0.0%)
MDR051 TARJ 63 1 60.87 (21.70) 0 (0.0%) 62 (98.4%) 1 (1.6%)
MDR052 YCJQ 48 2 91.08 (10.57) 0 (0.0%) 48 (100.0%) 0 (0.0%)
MDR053   48 0 50.84 (14.22) 0 (0.0%) 48 (100.0%) 0 (0.0%)
MDR054 YDJL 46 1 93.70 (12.44) 0 (0.0%) 46 (100.0%) 0 (0.0%)
MDR055   44 0 63.84 (10.29) 0 (0.0%) 44 (100.0%) 0 (0.0%)
MDR056   44 0 63.41 (20.64) 0 (0.0%) 44 (100.0%) 0 (0.0%)
MDR057 BCHC 43 2 61.89 (8.07) 0 (0.0%) 43 (100.0%) 0 (0.0%)
MDR058   43 0 76.53 (11.52) 0 (0.0%) 43 (100.0%) 0 (0.0%)
MDR059   42 0 56.97 (9.37) 0 (0.0%) 42 (100.0%) 0 (0.0%)
MDR060 YPHC 42 1 84.08 (22.01) 0 (0.0%) 42 (100.0%) 0 (0.0%)
MDR061 bBDH 40 0 63.33 (22.56) 0 (0.0%) 40 (100.0%) 0 (0.0%)
MDR062 CCR2 40 0 73.01 (14.76) 0 (0.0%) 40 (100.0%) 0 (0.0%)
MDR063   38 0 58.21 (20.04) 0 (0.0%) 38 (100.0%) 0 (0.0%)
MDR064   33 0 81.63 (18.31) 0 (0.0%) 33 (100.0%) 0 (0.0%)
MDR065   32 0 53.79 (11.72) 0 (0.0%) 31 (96.9%) 1 (3.1%)
MDR066   32 1 82.45 (18.25) 0 (0.0%) 32 (100.0%) 0 (0.0%)
MDR067 bQOR 32 0 73.92 (21.12) 0 (0.0%) 32 (100.0%) 0 (0.0%)
MDR068   32 0 55.05 (10.93) 0 (0.0%) 32 (100.0%) 0 (0.0%)
MDR069   32 0 54.76 (13.41) 0 (0.0%) 30 (93.8%) 2 (6.2%)
MDR070   31 0 50.14 (19.08) 0 (0.0%) 31 (100.0%) 0 (0.0%)
MDR071   31 0 52.17 (11.37) 0 (0.0%) 31 (100.0%) 0 (0.0%)
MDR072 bDHSO 31 1 65.28 (20.13) 0 (0.0%) 31 (100.0%) 0 (0.0%)
MDR073 bQOR2 31 0 81.84 (19.40) 0 (0.0%) 31 (100.0%) 0 (0.0%)
MDR074   30 0 79.07 (19.18) 0 (0.0%) 30 (100.0%) 0 (0.0%)
MDR075   29 0 82.92 (18.37) 0 (0.0%) 29 (100.0%) 0 (0.0%)
MDR076   29 0 57.41 (13.46) 0 (0.0%) 29 (100.0%) 0 (0.0%)
MDR077   28 0 58.92 (10.41) 0 (0.0%) 24 (85.7%) 4 (14.3%)
MDR078 RhobDH 25 0 55.27 (11.23) 0 (0.0%) 25 (100.0%) 0 (0.0%)
MDR079   25 0 63.69 (12.82) 0 (0.0%) 25 (100.0%) 0 (0.0%)
MDR080 bPDH 24 0 75.24 (15.12) 0 (0.0%) 24 (100.0%) 0 (0.0%)
MDR081   23 0 53.96 (19.57) 0 (0.0%) 23 (100.0%) 0 (0.0%)
MDR082   23 0 63.98 (10.48) 0 (0.0%) 23 (100.0%) 0 (0.0%)
MDR083   21 0 57.76 (20.40) 0 (0.0%) 9 (42.9%) 12 (57.1%)
MDR084   21 0 44.68 (12.83) 0 (0.0%) 21 (100.0%) 0 (0.0%)
MDR085   21 0 68.74 (15.71) 0 (0.0%) 21 (100.0%) 0 (0.0%)
MDR086 MycDH 20 0 65.99 (28.08) 0 (0.0%) 20 (100.0%) 0 (0.0%)
  1. This table shows properties of the MDR families for which we have derived HMMs, including its assigned name (if any), size, number of members in the Swiss-Prot database, average percent pairwise sequence identities in the family (and sample standard deviation) and distribution of members over the kingdoms of life (and proportions). See also Additional file 2: mdr-properties for further data. Empty name fields indicate families where the function has not yet been established for any of the members.