Table 3 Summary of zebrafish OPEN ZFN target sites, classified by ZiFOpT
From: Predicting success of oligomerized pool engineering (OPEN) for zinc finger target site sequences
Confidence Score (Active Sites) | False Positive Rate1 (FPR) | # of zebrafish transcripts targeted2 | Average # of ZFN target sites2 in transcripts containing nuclease sites | # of potential target sites2 eliminated by using ZiFOpT | ||
|---|---|---|---|---|---|---|
** | ** | 25,174 | (86%) | 4.5 | 0 | (0%) |
> 4 | 24% | 15,565 | (53%) | 2.3 | 78,934 | (69%) |
> 6 | 14% | 12,622 | (43%) | 2.0 | 89,580 | (78%) |
> 8 | 7% | 6,942 | (24%) | 1.5 | 103,877 | (90%) |