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Table 3 Summary of zebrafish OPEN ZFN target sites, classified by ZiFOpT

From: Predicting success of oligomerized pool engineering (OPEN) for zinc finger target site sequences

Confidence Score (Active Sites) False Positive Rate1 (FPR) # of zebrafish transcripts targeted2 Average # of ZFN target sites2 in transcripts containing nuclease sites # of potential target sites2 eliminated by using ZiFOpT
** ** 25,174 (86%) 4.5 0 (0%)
> 4 24% 15,565 (53%) 2.3 78,934 (69%)
> 6 14% 12,622 (43%) 2.0 89,580 (78%)
> 8 7% 6,942 (24%) 1.5 103,877 (90%)
  1. 1estimated from training data 2in coding exons 1-3 **no classification