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Figure 1 | BMC Bioinformatics

Figure 1

From: Assessment and optimisation of normalisation methods for dual-colour antibody microarrays

Figure 1

Loess curves according to global loess (GL), rank-invariant loess (InvTseng), modified rank-invariant loess (InvMod) and rank difference weighted global loess (RDWGL) normalisation. The selected rank-invariant proteins are shown in green. To illustrate the effect of a strong upregulation, the 40% of proteins simulated as being upregulated were generated by random draws from a N(0.3, 0.1) distribution left-truncated at zero and are shown in red.

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