Figure 5

Comparison of our topological clustering method and Resnik (MAX) as scoring positive and negative PPIs. The scatter plot of semantic similarity scores for positive (red) and negative (green) interactions. Semantic similarity scores range between 0.0 and 1.0 for both methods, with 1.0 being the best. A significant number of positive interactions are under-scored by Resnik (MAX) in all three ontologies compared to TCSS.