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Table 1 Performance of available tools and TESTLoc on plant EST-peptides1

From: TESTLoc: protein subcellular localization prediction from EST data

Predictors chl2 cyt end ext mit nuc per pla vac
  SN PPV SN PPV SN PPV SN PPV SN PPV SN PPV SN PPV SN PPV SN PPV
TargetP 19 62      29 25 18 44         
Protein Prowler 14 66      34 32 26 60    25 100     
BaCelLo 61 69 50 28    60 32 9 90 88 39       
Wolf-PSORT 27 41 60 27 0 0 18 36 8 58 65 71 16 50 0 0 0 0
YLoc 25 77 84 13 22 13 52 98 35 84 82 80 50 26 0 0 15 31
KnowPred NA NA 71 23 0 0 23 36 61 49 86 40 58 54 0 0 NA NA
MultiLoc2 14 81 84 12 9 8 44 48 18 37 48 67 67 10 0 0 45 54
BLAST3 76 97 77 62 64 100 81 95 57 87 77 96 25 60 0 0 0 0
TESTLoc 99 99 50 88 20 20 71 98 86 71 75 96 50 21 30 5 63 100
  1. 1 Numbers in %. Bold numbers are the result of the here described TESTLoc, which is tailored for ESTs. The results of full-length proteins are compiled in Additional file 8
  2. 2 Abbreviations: chl, chloroplast; cyt, cytosol; end, endoplasmatic reticulum; ext, extracellular space; mit, mitochondrion; nuc, nucleus; per, peroxisome; pla, plasma membrane; vac, vacuole; SN, sensitivity; PPV, positive predictive value
  3. 3 Note that all test data have homologs in databases, which in practice is rarely the case; see text