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Figure 4 | BMC Bioinformatics

Figure 4

From: Genome scale prediction of substrate specificity for acyl adenylate superfamily of enzymes based on active site residue profiles

Figure 4

Consensus Active Site Profile for six subfamilies. The table lists the conservation pattern of 15 positions that constitute the SDRs for various subfamilies. Number in the bracket refers to the percentage conservation of the amino acid in the alignment. The positions which have conservation >80% or <50% are shown in red and green respectively. Those positions with conservation between 50% and 80% are colored in pink. The positions which are highlighted have a subfamily specific conservation pattern and play a crucial role in controlling substrate specificity. Position number 210 (highlighted in yellow) was identified by docking studies.

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BMC Bioinformatics

ISSN: 1471-2105

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